Discussion on clinical rational use of shuganning injection and its adverse reactions
Objective To analyze the adverse reaction of shuganning injection as well as clinical rational drug use.Methods A total of 1000 cases treated with shuganning injection from January 2020 to December 2021 were selected as the study subjects,and their drug use was retrospectively analyzed.Corresponding departments and age groups were counted,unreasonable problems of clini-cal drug use were summarized,and the occurrence time and specific manifestations of adverse reactions were analyzed.Results The highest usage rate of shuganning injection was at the department of hepatobiliary surgery,accounting for 36.50％,and the highest fre-quency of use was from 41 to 60 years old,accounting for 41.50％.Among 1000 patients,the irrational clinical use of injection ac-counted for the highest proportion of inappropriate combination of drug use(13.10％),followed by the non use of solvent recommended by the instruction manual(9.30％).In terms of adverse reaction time,a short time is 0.5h,the long time is more than 7d,most of them were concentrated within 0.5h,The drug could involve the skin system and its mucosa,circulatory system,as well as the respiratory sys-tem,and the specific manifestations were papules,skin pruritus,chest tightness and so on.Conclusion The problem of unreasonable use of shuganning injection is still open and needs to be strengthened,so as to improve the rational of drug use.
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