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乌鲁木齐某社区Hcy分布特征及影响因素分析

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目的 为了解乌鲁木齐某社区居民同型半胱氨酸(Hcy)分布特点,分析高同型半胱氨酸血症(HHcy)患病率及相关影响因素.方法 对2021年7至12月间乌鲁木齐某社区体检人群进行横断面研究,将符合课题要求受试者统计性别、年龄,采集血样并检测Hcy、叶酸水平,分析不同性别、不同年龄Hcy、叶酸水平差异,分析与Hcy相关性.结果 乌鲁木齐市某社区居民中,男性叶酸均值低于女性叶酸均值(P<0.05);男性Hcy中位数水平高于女性(P<0.001);女性绝经后Hcy高于绝经前(P<0.05);随叶酸升高,Hcy呈下降趋势,两者呈负相关性.结论 乌鲁木齐市某社区居民同型半胱氨酸较高,男性Hcy普遍高于女性,男性叶酸普遍低于女性;年龄、女性是否绝经、叶酸是同型半胱氨酸影响因素.
Analysis of homocysteine distribution and related influencing factors in a community of Urumqi
Objective To investigate the distribution characteristics of homocysteine(Hcy)among residents in a community in Urumqi,and to analyze the prevalence of hyperhomocysteinemia(HHcy)and its related effects.Methods A cross-sectional study was conducted on the physical examination population in a community in Urumqi fromJuly 2021 to December 2021.At first,the gender and age of the subjects meeting the requirements of the subject were counted.Next,the blood samples were collected.Then,Hcy and folic acid levels were detected.Later,the differences in Hcy and folic acid levels of different genders and ages were analyzed.Finally,the correlation between folic acid and Hcy was analyzed.Results The mean value of the folate of males was lower than that of females(P<0.05).The median level of Hcy of males was higher than that of females(P<0.001).Hcy in postmenopausal women was higher than that in premenopausal women(P<0.05).With the increase of folate,Hcy showed a downward trend,and the two showed a negative cor-relation.Conclusion The level of homocysteine among residents in the community of Urumqi was high.The homocysteine level in males was generally higher than that in females.The folate level in males was generally lower than that in females.Age,menopause and folic acid levels were the factors that influenced homocysteine.

hyperhomocysteinemiahomocysteinefolateanalysis of influencing factors

李璇、李辉、蒋桂花、朱熠、陈纪轩、高霞

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新疆医科大学,乌鲁木齐 830054

新疆生产建设兵团医院,乌鲁木齐 830002

高同型半胱氨酸血症 同型半胱氨酸 叶酸 影响因素分析

2024

新疆医学
新疆维吾尔自治区医学会

新疆医学

影响因子:0.385
ISSN:1001-5183
年,卷(期):2024.54(5)