Analysis of TORCH infection in pregnant women and newborns in Aksu Region of Xinjiang from 2015 to 2021
Objective To investigate the trend of TORCH infection in pregnant women and newborns in Aksu Region of Xinjiang from 2015 to 2021,and to analyze the characteristics of TORCH infection in pregnant women and newborns.Methods The clinical da-ta of 4349 pregnant women and 4058 matched newborns screened for TORCH infection in Aksu of Xinjiang from 2015 to 2021 were an-alyzed retrospectively,The TORCH-IgM antibodies and IgG antibodies were detected and the positive rate of TORCH-IgM antibody and IgG antibodies of pregnant women of different ages were analyzed,and the positive rate of TORCH-IgM antibody in pregnant wom-en with normal pregnancy and adverse pregnancy were compared.Results TORCH infections among 4349 cases decreased from 2015 to 2021.The total positive rate of TORCH-IgM was 2.23%(97/4349)and that of TORCH-IgG was 3.66%(159/4349).The positive rate of rubella virus(RV)and cytomegalovirus(CMV)IgG antibodies was higher than that of toxoplasma toxoplasma(TOX)and herpes sim-plex virus(HSV)(P<0.05).TORCH infection in 4058 newborns showed a decreasing trend from 2015 to 2021.The total positive rate of TORCH-IgM was 1.75%(71/4058)and that of TORCH-IgG was 1.82%(74/4058).There was no significant difference in the posi-tive rates of IgM and IgG antibodies(P>0.05).Among 4349 pregnant women,the total positive rate of TORCH-IgM antibody was 0.78%(34/4349),and the positive rate of CMV was the highest,accounting for 76.47%of the total positive cases.The positive rate of TORCH-IgM antibody in prenatal cord blood in adverse pregnancy group was higher than that in normal pregnancy group,and the dif-ference was statistically significant(P<0.05).The positive rates of HSV-IgM antibody and RV-IgG antibody in pregnant women≤35 years old were higher than those in pregnant women>35 years old,but the positive rates of CMV-IgG and HSV-IgG antibodies were lower than those in pregnant women>35 years old,with statistical significance(P<0.05).There was no significant difference in the positive rates of TOX-IgM,RV-IgM,CMV-IgM and TOX-IgG antibodies among pregnant women in different age groups(P>0.05).Conclusion From 2015 to 2021,the infection rate of TORCH in Aksu region of Xinjiang,gradually decreased.CMV is the main patho-gen of infection in pregnant women and newborns,and the positive rate of HSV-IgM was mainly in young pregnant women,so pre-preg-nancy TORCH test should be strengthened to reduce the infection rate.
Pregnant womennewbornTORCH infectionImmunoglobulin M antibodyImmunoglobulin G antibody
NETL
NSTL
万方数据
