新疆乌鲁木齐市某三甲医院皮肤性病科泌尿生殖系统感染患者三种病原体检测分析
Detection and analysis three kinds of pathogen in the patients with urogenital system infection in dermatology department of a tertiary hospital in Urumqi,Xinjiang
赵娟 1李婷婷 1关猛猛 1丁媛 1康晓静1
作者信息
- 1. 新疆维吾尔自治区人民医院皮肤性病科,新疆皮肤性病临床医学研究中心,新疆皮肤病研究重点实验室,乌鲁木齐 830001
- 折叠
摘要
目的 总结1094例泌尿生殖系统感染患者淋病奈瑟菌(NG)、沙眼衣原体(CT)及支原体感染特点,为临床诊治及疾病预防与宣教提供依据.方法 平板培养法检测NG,乳胶法检测CT,改良肉汤法检测支原体.结果 三种病原体总阳性检出率为40.95%,NG、CT及支原体阳性检出率分别为13.45%,1.99%,29.00%,单项病原体阳性检出率显著高于混合感染(P＜0.01).四年间,NG,CT感染人数无明显变化,支原体感染及NG合并支原体感染人数呈上升趋势(P＜0.01;P＜0.05).男性NG阳性检出率显著高于女性(P＜0.01),女性支原体阳性检出率显著高于男性(P＜0.01).小于20岁患者NG阳性检出率最高(31.03%,P＜0.01).解脲脲原体(Uu)阳性检出率显著高于人型支原体(Mh)及合并感染(P＜0.01).药敏结果显示,氟喹诺酮类药物存在较高的耐药性,大环内酯类具有较高的敏感性.结论 NG、CT阳性检出率保持平稳,支原体及NG伴发支原体感染呈逐年上升趋势.NG感染患者多集中于20岁以下男性.支原体感染以女性患者居多,氟喹诺酮类存在较高的耐药性.
Abstract
Objective To analyze the characteristics of Neisseria gonorrhoeae(NG),Chlamydia trachomatis(CT)and mycoplasma infection in 1094 patients with urogenital system infection,and provide evidence for clinical diagnosis and treatment,disease preven-tion and education.Methods The plate culture method was used to detect NG,the latex method was used to detect CT,and the im-proved broth method was used to detect mycoplasma.Results The total positive detection rate of three kinds of pathogen was 40.95%.The positive detection rates of NG,CT and mycoplasma were 13.45%,1.99%,and 29.00%,respectively.The single infection rate was significantly higher than the mixed infection rate(P＜0.01).In the past four years,the number of NG and CT infections did not change significantly,and the number of mycoplasma infections and NG combined with mycoplasma infections showed an upward trend(P＜0.01,P＜0.05).The NG infection rate of male patients was significantly higher than that of female patients(P＜0.01),the mycoplasma infection rate of female patients was significantly higher than that of male patients(P＜0.01).The positive detection rate of NG was the highest in patients under 20 years old(31.03%,P＜0.01).The infection rate of Mycoplasma urealyticum(Uu)was significantly higher than that of Mycoplasma hominis(Mh)and Uu combined with Mh mixed infection(P＜0.01).The drug susceptibility results showed that fluoroquinolones had high drug resistance,and macrolides had high sensitivity.Conclusion The positive detection rate of NG and CT remained stable,and the infection of mycoplasma and NG accompanied with mycoplasma showed an increasing trend year by year.NG infection patients mostly concentrated in male under 20 years old.Most of the patients with mycoplasma infection are female,and there is high resistance to fluoroquinolones.
关键词
泌尿生殖系统感染/淋病奈瑟菌/沙眼衣原体/支原体Key words
urogenital system infection/Neisseria gonorrhoeae/Chlamydia trachomatis/Mycoplasma引用本文复制引用
基金项目
新疆维吾尔自治区自然科学基金(2020D01C126)
新疆维吾尔自治区人民医院院内项目(20200301)
出版年
2024
NETL
NSTL
万方数据