Meta analysis of high-intensity focused ultrasound treatment for benign thyroid nodules
Objective To evaluate the effectiveness of high-intensity focused ultrasound in the treatment of benign thyroid nodules using meta-analysis.Method According to the inclusion and exclusion criteria,research literature on the treatment of benign thyroid nodules using high-intensity focused ultrasound published between the establishment of the database and December 2023 was screened from the database,and its therapeutic effects were further analyzed using meta-analysis.Result Out of 172 research articles,10 articles were selected regarding the use of high-intensity focused ultrasound to treat benign thyroid nodules.The postoperative VRR was 20.33%(95%CI:10.71-29.96%,I2=0%,P<0.0001)at 1 month follow-up,37.44%(95%CI:30.17-44.71%,I2=20%,P<0.0001)at 3 months follow-up,and 41.42%(95%CI:34.13-48.71%,I2=52%,P<0.0001)at 6 months follow-up.The VRR at 1-year follow-up was 38.75%(95%CI:31.83-45.68%,I2=76%,P<0.0001),and at 2-year follow-up it was 34.22%(95%CI:28.45-39.98%,I2=78%,P<0.0001).Conclusion High intensity focused ultrasound is a new feasible method for treating benign thyroid nodules.