联合用药在老年无痛胃镜检查患者中的应用
The effect of dacronin hydrochloride and dimethylsiloxane combined with chymotrypsinin painless gastroscopy
周旋 1王红 1李小倩 1冯霞2
作者信息
- 1. 郑州市第七人民医院,郑州 450006
- 2. 郑州市人民医院,郑州 450006
- 折叠
摘要
目的 探讨盐酸达克罗宁与二甲硅油联合糜蛋白酶在行无痛胃镜检查老年患者中的应用效果.方法 选取2021年1月-2021年3月在郑州市第七人民医院接受无痛胃镜检查的1379例的门诊及住院患者作为研究对象,按照随机性原则将其分为对照组689例和研究组690例.对照组检查前口服盐酸达克罗宁胶浆,研究组患者检查前口服二甲硅油散和糜蛋白酶溶液.比较两组胃镜检查时视野清晰度、微小病变检出情况、癌前病变等情况.结果 研究组患者检查视野清晰度相比对照组均明显降低,比较差异均有统计学意义(P＜0.05);研究组患者平均胃镜检查时间相比对照组明显缩短,比较差异有统计学意义(P＜0.001);研究组患者微小病变和癌前病变的检出率均明显多于对照组,比较差异均有统计学意义(P＜0.05);研究组患者平均麻醉药物用量相比对照组明显减少(P＜0.001);结论 二甲硅油联合糜蛋白酶应用于无痛胃镜检查的患者中能更好地消除黏膜表面的起泡黏液,提高癌前病变和早期胃癌的检出率.
Abstract
Objective To investigate the effect of dacronin hydrochloride and dimethylsiloxane combined with chymotrypsin in painless gastroscopy in elderly patients.Methods A total of 1379 outpatients and inpatients who received painless gastroscopy in our hospital from January 2021 to March 2021 were selected as the research objects,and they were divided into control group(689 cases)and research group(690 cases)according to the randomness principle.The control group was orally treated with dacronine hydrochlo-ride gum slurry before examination,while the study group was orally treated with dimethylsilicone oil powder and chymotrypsin solution before examination.The sharpness of field of vision,detection of small lesions and precancerous lesions were compared between the two groups.Results The visual field definition of patients in the study group was significantly lower than that in the control group,with statistical significance(P<0.05).The average time of gastroscopy in the study group was significantly shorter than that in the control group,and the difference was statistically significant(P<0.001).The detection rates of microlesions and precancerous lesions in the study group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).The average amount of anesthetic drugs in the study group was significantly reduced compared with that in the control group(P<0.001).Conclusion Dimethylsiloxane combined with chymotrypsin can better eliminate foaming mucus on mucosal surface and improve the detection rate of precancerous lesions and early gastric cancer in patients undergoing painless gastroscopy.
关键词
无痛胃镜/二甲硅油/糜蛋白酶/盐酸达克罗宁/视野清晰度Key words
painless gastroscopy/Dimethylsiloxane/Chymotrypsin/Dyclonine hydrochloride/Clear vision引用本文复制引用
出版年
2024
NETL
NSTL
万方数据