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妊娠期糖尿病发生的影响因素及母婴结局分析

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目的 观察妊娠期糖尿病(GDM)孕妇的不良妊娠结局并分析与其相关的危险因素,以改善患者母婴结局.方法 选取安阳市妇幼保健院2021年10月至 2023年2月收治的GDM孕妇128例和非GDM孕妇105例.采用单因素和二元Logistic回归分析两组患者发生不良妊娠结局的危险因素.比较两组孕妇的母婴结局.结果 128例GDM孕妇中,母亲不良妊娠结局发生率为46.09%.剖宫产率为53.91%,且GDM组和非GDM组患者年龄≥35岁、BMI≥24 kg/m2、阴道念珠菌感染、糖尿病家族史、乙型肝炎表面抗原阳性、多囊卵巢综合征比较,差异有统计学意义(P<0.05).多因素Logistic回归结果显示,年龄≥35岁、BMI≥24 kg/m2、糖尿病家族史、乙型肝炎表面抗原阳性均为孕产妇发生GDM不良妊娠结局的独立危险因素(OR=3.88、3.75、4.96、3.10,P<0.05).结论 应严密关注GDM孕妇发生不良妊娠结局的危险因素,并在孕期积极进行相应干预,降低孕妇发生不良妊娠结局的概率,利于患者改善母婴结局.
Analysis of influencing factors and maternal and infant outcomes of gestational diabetes mellitus
Objective To observe the adverse pregnancy outcome of pregnant women with gestational diabetes(GDM)and analyze its related risk factors,so as to improve the maternal and infant outcomes of patients with GDM.Methods 128 pregnant women with GDM and 105 pregnant women without GDM were selected from Anyang Maternal and Child Health Hospital from October 2021 to February 2023.The risk factors of adverse pregnancy outcomes were analyzed by univariate and binary Logistic regression.The mater-nal and infant outcomes of the two groups were compared.Results Among 128 GDM pregnant women,the incidence of adverse preg-nancy outcome was 46.09%.The cesarean section rate was 53.91%,and there were statistically significant differences between GDM group and non-GDM group in age≥35 years,BMI≥24 kg/m2,vaginal candida infection,family history of diabetes,positive hepatitis B surface antigen,and polycystic ovary syndrome(P<0.05).Multivariate Logistic regression results showed that age≥35 years old,BMI≥24 kg/m2,family history of diabetes,positive hepatitis B surface antigenwere all independent risk factors for adverse pregnancy out-comes with GDM(OR=3.88,3.75,4.96,3.10,P<0.05).Conclusion Strict attention should be paid to the risk factors for adverse preg-nancy outcomes in GDM pregnant women,and corresponding interventions should be actively carried out during pregnancy to reduce the probability of adverse pregnancy outcomes in pregnant women and help patients improve maternal and infant outcomes.

Gestational diabetes mellitusRisk factorsMaternal and infant outcome

孙蓉、张佳、刘艳

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河南省安阳市妇幼保健院病理产三科,河南 安阳 455000

妊娠期糖尿病 危险因素 母婴结局

2024

新疆医学
新疆维吾尔自治区医学会

新疆医学

影响因子:0.385
ISSN:1001-5183
年,卷(期):2024.54(9)