To explain the global distribution of suicide rates,this study is based on publicly available data from authoritative sources such as the World Health Organization.It proposes and tests a conceptual model that incorporates the co-evolution of collectivist culture and the 5-HTTLPR S allele as explanatory factors.The analysis reveals that collectivist culture and the prevalence of depressive disorders serve as sequential mediators between the population proportion of individuals carrying the 5-HTTLPR S allele and suicide rates.The hypothesis of co-evolution between collectivist culture and 5-HTTLPR S allele has gained preliminary support,that is,collectivist culture may buffer the negative impact of carrying 5-HTTLPR S allele on individuals and groups,reducing regional prevalence of depressive disorders and suicide rates.
关键词
自杀率/集体主义文化/5-HTTLPR/S等位基因/协同进化/抑郁障碍
Key words
suicide rate/collectivism/5-HTTLPR S allele/co-evolution/depressive disorder