Motivation deficits in physical effort or cognitive effort expenditure?Evaluation of effort-based reward motivation and application of computational modeling in depression
Motivation deficits are a common symptom of depression,leading to abnormal reward assessment or experience in individuals with depression.Understanding the cognitive neural mechanisms of the willingness to expend cognitive or physical effort to obtain rewards is essential for helping patients recover their social functioning.However,research in this area is currently hindered due to a lack of appropriate methods for determining the roles of cognitive and physical effort expenditure in motivation deficits.By using experimental methods and cognitive computational models to distinguish and assess'cognitive effort'and'physical effort'decision-making in individuals with depression,we can further explore the essence of motivation deficits from the perspective of'reward for effort'and better understand the impact of motivation deficits on the disease state.