In recent years, many health damage incidents caused by cosmetic in consumers gave rise to high attention of cosmetic safety. Cosmetic is one kind of daily necessarily use product,its safety is very important. Only after ensuring safety, its effective, performance and stability could be considered. The risk factors of cosmetics safety may be caused by different reasons, such as raw materials in formula, microbe contamination, and using high risk substances, etc. It is better to take different prevention measures for different risk factors.