香料香精化妆品2024，Issue(1) ：67-73,164.DOI:10.20099/j.issn.1000-4475.2023.0199

大豆提取物-α-倒捻子素复合物的制备及其抗氧化活性

Preparation and Antioxidant Activity of Soybean Extract-α-Mangostin Complex

张余 王鹏 王雪峰 郭若曦 张蕾 王艳
香料香精化妆品2024，Issue(1) ：67-73,164.DOI:10.20099/j.issn.1000-4475.2023.0199
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大豆提取物-α-倒捻子素复合物的制备及其抗氧化活性

Preparation and Antioxidant Activity of Soybean Extract-α-Mangostin Complex

张余 1王鹏 2王雪峰 2郭若曦 2张蕾 2王艳1
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作者信息

  • 1. 天津中医药大学,天津 301617;现代中医药海河实验室,天津 301600
  • 2. 天津尚美化妆品有限公司,天津 300385
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摘要

为提高难溶化合物α-倒捻子素溶解性,采用摇瓶-冷冻干燥法制备大豆提取物-α-倒捻子素复合物并对其进行结构表征和体外抗氧化活性评价.结果表明,在最佳工艺即大豆提取物质量浓度 200 mg/mL、60℃、16 h、220 r/min下制得的复合物中α-倒捻子素溶解度为 379.014 μg/mL;复合物平均粒径为(1.21±0.015)nm,分布均一,且大豆提取物与α-倒捻子素之间可能通过氢键缔合;大豆提取物与α-倒捻子素具有协同抗氧化作用,大豆提取物-α-倒捻子素复合物对DPPH自由基和ABTS自由基清除作用强于同质量浓度的α-倒捻子素.

Abstract

In order to improve the solubility of α-mangostin,the soybean extract-α-mangostin complex was established by shaking flask-freeze-drying method,and its structure was characterized and its antioxidant activity was evaluated in vitro.The results showed that the solubility of α-mangostin was 379.014 μg/mL under the optimum preparation conditions of soybean extract 200 mg/mL,60℃,16 h and 220 r/min.The average particle size of the complex was(1.21±0.015)nm,with uniform distribution,and the association between soybean extract and α-mangostin might be achieved through hydrogen bond.In addition,soybean extract and α-mangostin had synergistic antioxidant activity,and the scavenging effect of soybean extract-α-mangostin complex on DPPH and ABTS free radicals was stronger than that of α-mangostin at the same concentration.

关键词

大豆提取物/α-倒捻子素/复合物/溶解度/抗氧化

Key words

soybean extract/α-mangostin/complex/solubility/antioxidant activity

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基金项目

国家自然科学基金青年科学基金项目(81602773)

出版年

2024
香料香精化妆品
上海香料研究所

香料香精化妆品

CSTPCD
影响因子：0.341
ISSN：1000-4475
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参考文献量14
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