Soothing and Moisturizing Effects of a Multi-Herb Extract
The soothing and moisturizing effects of a multi-herb extract prepared from Olea europaea leaf extract,Sophora flavescens root extract,Citrus reticulata fruit extract and Crocus sativus flower extract on sensitive skin were studied.By testing physical and chemical properties of the multi-herb extract,the mass fraction of hydroxytyrosol was 0.63%,and the mass concentrations of total flavonoids and phenols were 10.2,9.6 mg/mL,respectively.Chicken embryo chorioallantoic membrane(CAM)test and human patch safety test proved that the multi-herb extract with a mass fraction of 10%was non-irritating.The in vitro efficacy test showed that the multi-herb extract efficiently inhibited the expressions of IL-1α,IL-6,TNF-α,PEG2,arachidonic acid(AA)and NF-κB protein.Therefore,the multi-herb extract can be used as a soothing and moisturizing ingredient in cosmetic formulations.
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