Efficacy of Four Plant Extracts and Their Composition on Inhibiting Sebum Secretion
The 4 plant extracts,Lophatherum gracile Brongn,Epilobium angustifolium L,Vitis vinifera L and Glycyrrhiza inflata Bat,were studied for their oil-control efficacy through in-vitro test on sebaceous gland cells and also in-vivo oil-control efficacy evaluation.The toxicity of the plant extracts on sebaceous gland cells were detected by CCK-8 assay,and the effects of those extracts on lipid content in sebaceous gland cells were detected by the Nile red staining.Meanwhile,the 4 plant extracts were compounded to study the effects of phyto essence on lipid synthesis of sebaceous gland cells,and the efficacy was compared with isotretinoin,a commonly used drug for sebum secretion abnormalities.The changes of neutral lipids in the sebaceous gland cells and the results of oil red staining showed that the phyto essence combination has the potential to inhibit sebum secretion.
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