The percutaneous absorption of cosmetics is a prerequisite for their efficacy.Among the methods to evaluate transdermal absorption,confocal Raman spectroscopy has been paid more attention because of its advantages:non-invasive testing process,less sample handling,in situ detection,layer by layer detection,etc.In vivo detection,sample handling is simple and non-destructive for in situ testing,while in vitro method enables relatively deeper skin depth testing.In this paper,applications of Raman spectroscopy in the field of cosmetics were summarized,and the existing research methods were classified in vivo and in vitro methods.In addition,the research field of transdermal drug delivery was discussed for reference.The innovation points and achievements among different methods were explored.The advantages,disadvantages and prospects of Raman spectroscopy in cosmetics were also analyzed and prospected.
关键词
经皮吸收/拉曼光谱/化妆品/在体检测/离体检测
Key words
transdermal absorption/Raman spectroscopy/cosmetics/in vivo detection/in vitro detection
维普
万方数据