Efficacy of Fullerene-Multi Molecular Weight Sodium Hyaluronate Compositions
The firming,soothing and repairing effects of sodium hyaluronate composition(S1),fullerene-medium molecular weight sodium hyaluronate composition(S2)and fullerene-multiple molecular weiht sodium hyaluronate composition(S3)were evaluated by in vitro cell experiments.The results showed that S1,S2,S3 promoted the expression of collagenⅠ and FLG,while S2 significantly promoted the expression of LOR.The above three compositions could significantly inhibit the expression of MMP-1,IL-6,TNF-α,NO and iNOS.In conclusion,S3 have more significant firming and soothing effects as cosmetic raw materials.