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皮肤屏障受损修护的测试方法

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为研究皮肤屏障受损修护的测试方法,采用手臂胶带剥脱法建立屏障物理性受损模型,经皮水分散失率(TEWL)、角质层水分含量作为检测指标,通过市售产品验证其可信度及适用范围,并与常规面部屏障受损开放性试验进行结果比较.结果表明皮肤屏障受损模型测试结果与人体面部屏障受损开放性方法一致(P<0.05),对霜、乳、液不同剂型化妆品适用(P<0.05).但手臂受损模型与面部开放性测试的改善程度没有明显的相关性,无法进行比较.
Test Methods for Repairing Damaged Skin Barrier
In order to study the skin barrier damage repair test method,the arm tape peeling method was used to establish the barrier physical damage model.The detection indicators were the transepidermal water loss(TEWL)and stratum corneum moisture content.Commercially available products verified their credibility and scope of application,and the results were compared with the conventional open test of facial barrier damage.The results showed that the test results of the skin barrier damage model were consistent with the open method of human facial barrier damage(P<0.05),and it was suitable for different dosage forms of cream,lotion,and liquid cosmetics(P<0.05).However,the arm injury model had no significant correlation with the degree of improvement in the facial openness test and could not be compared.

evaluation methodskin barrierdamage modelrepair

邓艳芳、刘前、张廷志

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拙燕检测技术(长沙)有限公司,湖南长沙 410000

水羊化妆品制造有限公司,湖南长沙 410000

评价方法 皮肤屏障 损伤模型 修护

2024

香料香精化妆品
上海香料研究所

香料香精化妆品

CSTPCD
影响因子:0.341
ISSN:1000-4475
年,卷(期):2024.(5)