Construction of a Model for Evaluating the Soothing and Repairing Effects on the Human Body after Chemical Peeling
After chemical peeling,the skin may experience side effects such as erythema,dryness,and sensitivity.At this time,skin care can alleviate the side effects and promote skin recovery.An increase in erythema index(EI)and transepidermal water loss(TEWL)was observed within 4 h after salicylic acid and glycolic acid peeling.Then 30 subjects were recruited to establish a model of soothing and repairing chemically peeled skin.The glycolic acid group showed increased EI at 1,2,3 h(P＜0.05),and increased TEWL at 2 d(P＜0.05).Intervention with products with soothing and repairing effects reduced both EI and TEWL,and the side effects were alleviated.The changes in indices between the blank and positive groups at some time points had statistical differences(P＜0.05).Therefore,the glycolic acid chemical peeling model can serve as a safe,stable,and effective human efficacy evaluation method to assist in the development of soothing and repairing skincare products after chemical peeling.
chemical peelingsoothingrepairinghuman body efficacy evaluation
万方数据
维普
