Objective To explore the diagnostic value and predictive factors of capsule endoscopy (CE) for chronic abdominal pain.Methods Retrospective analysis was made on the clinical data on 206 patients who had been suffering chronic abdominal pain and had received CE examination in our hospital from Jun.2008 to Oct.2014 (males=125;females=81).Results In 206 cases,pathologic changes were found in 76 ones,with a detection rate of 36.9%,including suspected Crohn's disease (CD) in 8 cases,non specific small-intestinal ulcer in 10 cases,non-specific inflammation in 16 cases,small-intestinal parasites in 7 cases,small-intestinal polyp in 9 cases,small-intestinal tumor in 3 cases,small-intestinal diverticulum in 2 cases,and vascular malformation in 21 cases.The time for CE to pass through the pylorus was 1-517 min,56.8 min averagely;the small-intestinal transit time was 49-568 min,273.3 min averagely.Univariate analysis showed that the detection rates of patients with and without diarrhea were 30% and 38% (P > 0.05);the detection rates of patients ≥ 50 years old and < 50 years old were 41.1% and 33.6%(P > 0.05),and the detection rates of patients with and without alarm symptoms were 58.1% and 33.1%(P < 0.01).Multivariate logistic regression analysis showed that the presence of alarm symptoms was an independent predictor for increased CE positive diagnostic rate (OR =2.611;95% CI=1.129-6.039).Capsule retentions occurred in three cases totally,but were discharged naturally.Conclusion CE has certain diagnostic value for chronic abdominal pain,especially for the patients with alarm symptoms,but the application value still needs further study.