首页|MPV和PLR与冠状动脉狭窄程度相关性研究

MPV和PLR与冠状动脉狭窄程度相关性研究

Study on the correlation of MPV and PLR with the severity of coronary artery stenosis

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目的 探讨平均血小板体积(MPV)和血小板/淋巴细胞比值(PLR)与冠状动脉狭窄程度的相关性.方法 收集医院收治的疑诊冠心病(CHD)患者315例作为研究对象,均进行MPV和PLR检测.按照是否患有CHD及冠状动脉狭窄程度不同,分析MPV和PLR检测结果,并对与冠状动脉狭窄程度的相关性进行考量.结果 CHD患者及非CHD患者在年龄、高血压史、糖尿病史、MPV和PLR比较,均具有显著差异(P<0.05).低Gensini得分组共纳入患者90例,高Gensini分组共纳入患者95例.单因素分析结果显示,年龄、高血压史、糖尿病史、高脂血症史、MPV和PLR均可影响Gensini得分增高(P<0.05);多因素分析结果显示,MPV和PLR为影响Gensini得分增高的独立危险因素.结论 MPV和PLR均与CHD存在相关性,对于冠状动脉狭窄程度的预测具有较高的价值.
Objective To explore the correlation of mean platelet volume (MPV) and platelet / lymphocyte ratio (PLR) with the severity of coronary artery stenosis (CAS).Methods A total of 315 patients with suspected coronary heart disease (CHD) to receive treatment in our hospital were selected as research subjects and all received MPV and PLR detection. According to the existence of CHD and the severity of CAS, the MPV and PLR detection results were analyzed and the correlation with the severity of CAS was considered. Results There were significant differences in age, history of hypertension, history of diabetes, and comparison between MPV and PLR among the patients with CHD and the non-CHD ones (P < 0.05). Single factor analysis between the low Gensini score group(n=90) and the high Gensini score group(n=95 ) showed that the age, history of hypertension, history of diabetes, hyperlipidemia, and MPV and PLR could all cause increase in Gensini scores (P < 0.05); Multi-factor analysis showed that MPV and PLR were the independent risk factors causing increase in Gensini scores.Conclusion MPV and PLR are correlated with CHD, and this is of highvalue in the prediction of CAS.

coronary heart diseasecoronary arterystenosisplatelet volumeplatelet / lymphocyte ratio

郝明、王琳

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714000陕西渭南,渭南市第二医院检验科

渭南市妇幼保健院检验科

冠心病 冠状动脉 狭窄 血小板体积 血小板/淋巴细胞比值

2017

西南国防医药
成都军区医学科学技术委员会

西南国防医药

CSTPCD
影响因子:0.672
ISSN:1004-0188
年,卷(期):2017.27(3)
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