Anesthetic effects of telazol and dexmedetomidine combination on red pandas
To evaluate the anesthetic effects induced by combination of telazol(tiletamine-zolazepam)and dexmedetomidine on red pandas,a total of thirty red pandas requiring body check and treatment were examined.Red pandas were anesthetized by in-tramuscular injection of telazol(2.0～3.0 mg/kg)combined with dexmedetomidine(20～40 μg/kg).Physiologic parameters including heart rate,respiratory rate,rectal temperature,pulse oxygen saturation,as well as sedative and analgesic effects were assessed.All groups showed clinically comparable rapid induction effects resulting in spontaneous lateral/sternal recumbency and loss of paw withdrawal reflex in 8 minutes.Notably,the duration of general anesthesia for this combination(3.0 mg/kg tel-azol and30 μg/kg dexmedetomidine)was(61.5±7.06)min,which was significantly greater than the other four groups(P<0.05).During anesthesia,the physiological values such as heart rate,respiratory rate,rectal temperature and pulse oxygen satu-ration were in normal reference range.Likewise,red pandas showed good sedation,analgesia and muscle relaxation during anes-thesia,conforming to moderate level of anesthesia to surgical operation level.No vomiting,apnea irregular breathing or any ad-verse events were indicated in all groups.At the end of treatment anesthesia was fully reversed by atipamezole.In summary,the telazol-dexmedetomidine combination provided an effective and stable anesthesia for red pandas,and the duration of anesthesia could be controlled by varying the dosage,which could meet the ideal clinical anesthesia requirements for general physical ex-amination,diagnosis and surgical treatment.
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