An Analysis of the Causes of Frequent Outbreaks of Plaguein the Eastern Mediterranean Cities in Late Antiquity
In the year of 541,the plaguebroke out in the Eastern Mediterranean area and quickly swept over the vast ma-jority of the Eastern Mediterranean world.The first outbreakof plagueand its subsequent recurrences caused serious im-pact on the Eastern Mediterranean cities,such as Constantinople,Antioch and Alexandria.Many large-scale outbreaks in the Eastern Mediterranean cities in Late Antiquity were directly related to the objective factor that plague was highly infectious and spread widely.Moreover,cities,which played an important role in the administrative,economic and mili-tary systems of the Eastern Mediterranean world,had a large population,crowded living environment and frequent ex-changes with the outside world.This was the significant factor why cities weredifficult to escape from the plague infec-tion circle.In addition,the level of science and technology and medical conditions during this period limited the proper understanding and treatment of the plague.As a result,the Eastern Mediterranean cities wererepeatedly thumped by the epidemic.Under the influence of frequent outbreaks of the epidemic,the Eastern Mediterranean cities had showed a trend of obvious decline and transformation.