Analysis of Influencing Factors for Deep Vein Thrombosis Formation in Patients with Central Venous Catheterization in the Intensive Care Unit
Objective To explore the incidence of deep vein thrombosis(DVT)and its influencing factors in critically ill patients with central venous catheterization.Methods A retrospective analysis was performed,encompassing 115 patients who un-derwent central venous catheterization procedures in our hospital's Emergency Intensive Care Unit(EICU).Patients were catego-rized into a thrombosis group and a non-thrombosis group based on the occurrence of DVT after catheterization.A comparative anal-ysis of clinical profiles was conducted,and factors with significant statistical disparities were subjected to multivariate analysis to i-dentify determinants influencing DVT development.The sensitivity and specificity of these factors in predicting DVT were assessed using the receiver operating characteristic(ROC)curve.Results Among 115 patients 24 developed DVT,and the top three types of thrombosis in DVT were simple intermuscular vein thrombosis,multiple deep vein thromboses in the lower limbs,and mural throm-bi.The top three diseases associated with DVT were acute respiratory infections,malignancies,and acute digestive hemorrhagic dis-eases.Significant statistical differences were observed between the two groups in terms of infection,malignancy,hyperlipidemia,history of thrombosis,duration of catheter retention,platelet count(PLT),prothrombin time(PT),and D-dimer levels(all P＜0.05).Multivariate analysis revealed that hyperlipidemia,thrombosis history,catheter retention duration,and D-dimer levels were independent risk factors for DVT in catheterized patients.ROC curve analysis indicated that both catheter retention duration and D-dimer levels are significant predictors of DVT,with the former showing the highest area under the curve(AUC=0.765)and an op-timal cutoffpoint of 2.5 days,offering the sensitivity and specificity of 85.7%and 57.1%,respectively,for DVT prediction.Con-clusion The incidence of DVT in critically ill patients with central venous catheterization is high,and it should be taken seriously in clinical practice.Hyperlipidemia,thrombosis history,catheter retention duration,and D-dimer levels are independent risk factors for DVT,among which the duration of catheter retention has the greatest value in predicting the formation of DVT.
Intensive care unitsCentral venous cathetersVenous thrombosisEmergency serviceLogistic models
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