Research Progress of Hippocampus in Pain and Depression Comorbidity
The hippocampus is an important region of the brain that plays a role in memory,emotions and stress respon-ses.Pain and depression often co-occur clinically,and pain often worsens depressive symptoms,and vice versa.Structural and functional changes in the hippocampus are considered to be important neurobiological mechanisms of pain and depression comor-bidity.This paper reviews the relationship between morphological and neurochemical changes in the hippocampus with depression,chronic pain and pain depression comorbidities.These studies provide a new perspective for understanding the pathophysiological mechanisms of pain and depression comorbidity,and provide the possibility for developing new treatment strategies.
Pain and depression comorbidityNeuroplasticity of hippocampusChronic painDepressed
国家科技期刊平台
NSTL
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