This study evaluates the efficacy of Compound Yinhua Oral Liquid in preventing and treating bacterial diarrhea in pig-lets.Separate trials were conducted on healthy neonatal piglets and nursing piglets with diarrhea.Compound Yinhua Oral Liquid demonstrated a preventive protection rate of 91.1%against neonatal piglet diarrhea,a 30.6%improvement over enfloxacin injec-tion.Additionally,when combined with Sihuang Zhili Keli,it achieved an overall effective rate of 88.2%in nursing piglets with bacterial diarrhea,representing a 35.9%enhancement over enfloxacin injection.These findings suggest that Compound Yinhua Oral Liquid offers a promising preventive effect against neonatal piglet diarrhea and can be used alongside Sihuang Zhili Keli for treating drug-resistant bacterial diarrhea in clinical settings.