Etomidate is a hypnotic agent used for induction of anesthesia,characterized by rapid onset,short duration,and hemodynamic stability.It is widely used for anesthesia induction in elderly patients and those with cardiovascular disease and critical illness.The"2021 China Drug Situation Report"issued by the National Narcotics Control Commission pointed out that there is a situation of abuse of"smoke powder"in some areas,and its main component,etomidate,is identified as a drug substitute.However,there have been no reports of etomidate-related deaths in China.This article reports a case of a minor who died from respiratory failure due to exacerbation of bronchopneumonia after inhaling etomidate,for reference by peers.In forensic practice,attention should be paid to the adverse reactions of etomidate and the abuse of etomidate.