Research Progress on the Detection of Mycotoxins and Their Metabolites in Biological Samples
Mycotoxins are secondary metabolites produced by phytopathogenic fungi under specific conditions.They are widely distributed in crops,and are chemically stable and highly toxic.In criminal cases,the detection of mycotoxins in biological samples can provide more accurate forensic evidence;therefore,the detection of mycotoxins in biological samples has gained great attention.In this study,common mycotoxins and their metabolites in biological samples are introduced,and pretreatment methods,such as liquid-liquid extraction,solid-phase extraction,and protein precipitation,are summarized.Detection methods,such as immunoassay,fluorescence assay,gas chromatography-mass spectrometry,and liquid chromatography-mass spectrometry,were reviewed,and the future of mycotoxins and metabolites detection in biological samples were prospected with the aim of providing information on the detection of mycotoxins in the field of forensic science.