This article takes Arabic and Persian as the research objects,starting from their history,and provides examples to illustrate the interaction and influence of these two languages with other langua-ges in Eurasia under the background of the Silk Road,from the perspectives of cognate words,borrowed words,literary exchanges,and literary relics.In Islamic languages,Persian and Arabic can be described as equally divided,forming two overlapping writing circles.Arabic,with its sacred position in Islam,has had a profound impact on the languages of Muslims in various regions,while Persian,with its brilliant lit-erary achievements,has left various traces in the languages of various ethnic groups in the Middle East and Central Asia.Whether it is a pile of literature or folk oral traditions,carefully searched,there is evidence of these language interactions everywhere,becoming a fascinating aspect of the Silk Road civilization ex-change.