In order to make the localization of proton Bragg peak in media more accurate,so as to be used in clinical tumor localization and treatment,a three-dimensional Bragg peak localization algorithm is pro-posed.The algorithm is based on frequency domain full waveform inversion algorithm and LTI algorithm to locate Bragg peak.In this paper,five target Bragg peak locations are selected,and then 10 initial Bragg peak locations are randomly selected within 50mm from the center with these 5 coordinates as the center.The final location error converges to 0.2mm~1.7mm,which can well meet the positioning accuracy re-quirements of proton therapy.
关键词
质子治疗/布拉格峰定位/三维介质/联合反演/频域全波形反演
Key words
proton therapy/Localization of Bragg Peak/three-dimensional medium/joint inversion/fre-quency domain full waveform inversion