激光加工镁合金表面形貌的生物相容性
Biocompatibility of Morphology on Laser-Processed Magnesium Alloy Surfaces
刘鹏 1郭璇 2高冬芳 3赵洋洋 4乔阳1
作者信息
- 1. 济南大学机械工程学院,山东济南 250022
- 2. 山东省青岛市市北区教育和体育局,山东青岛 266022
- 3. 山东大学第二医院 基础医学研究所,山东 济南 250033
- 4. 山东大学第二医院创伤骨科,山东济南 250031
- 折叠
摘要
对镁合金表面进行激光加工改性,通过观察羊肋骨表面形貌,确定激光刻蚀形貌为沟槽.通过接触角测试,探究镁合金表面不同形貌的润湿性.通过细胞粘附试验,探究不同形貌的镁合金表面对细胞粘附、生长、迁移的影响.结果表明,田形形貌润湿角比沟槽形貌小,田形形貌的镁合金表面有更好的亲水性;与光滑表面相比,田形表面细胞附着性好,凹陷及凸起处均铺满细胞,这说明经过激光加工处理获得的显微图案有利于生物相容性的提高.
Abstract
The surface of magnesium alloy was laser-processed,and the laser-etched morphology was determined as grooves by observing the surface morphology of sheep rib bone.The wettability of different morphologies was investigated by contact angle test.Through the cell adhesion test,the effects of different morphologies on cell adhesion,growth and migration were investigated.Results show that the wetting angle of the block-shaped surface is smaller than that of the groove-shaped surface,and block-shaped surface has better hydrophilicity.Compared with the smooth surface,the block-shaped surface has better cell adhesion,and the depressions and bumps are full of cells,suggesting that the micropatterns prepared by the laser processing are conducive to the enhancement of biocompatibility.
关键词
镁合金/激光表面改性/仿生/润湿性/细胞粘附Key words
magnesium alloy/laser surface modification/bionic/wettability/cell adhesion引用本文复制引用
出版年
2024
NETL
NSTL
万方数据