合并心血管疾病的高血压患者强化降压治疗研究进展
Advances in intensive antihypertensive treatment in hypertensive patients complicated with cardiovascular disease
张茸祯 1贾敏 2娄豆豆 1王霄霄 1王亮 3王汝涛 1陶凌1
作者信息
- 1. 710000 西安,空军军医大学西京医院心内科
- 2. 710000 西安,空军军医大学西京医院心内科;710032 西安,空军军医大学基础医学院生理与病理生理学教研室
- 3. 250200 济南,济南市章丘区人民医院心内科
- 折叠
摘要
高血压是世界范围内的一个严重公共卫生问题,是心血管疾病的主要危险因素,高血压患者常合并多种心血管疾病,积极控制高血压可有效改善合并心血管疾病患者的临床预后.2023 年 6 月《ESH高血压管理指南》发布,更新了启动降压治疗时机的推荐,对于既往有心脑血管疾病的正常高值血压的患者,指南建议从 130/80 mmHg启动降压治疗.2023 版《中国高血压防治指南》也建议,心血管风险为高危和很高危的高血压患者目标血压可进一步降至 130/80 mmHg以下.这提示强化血压控制在合并心血管疾病的高血压患者中可以取得更大的临床获益.近年来多项研究显示了对高血压患者强化血压控制的优势,该文总结了合并不同心血管疾病的高血压人群中强化血压控制的相关临床研究进展,为此类患者临床强化降压治疗提供依据.
Abstract
Hypertension is a serious public health problem worldwide and a major risk factor for cardiovascular disease.Hypertensive patients are constantly complicated with cardiovascular disease.Effective blood pressure control could improve clinical prognosis of these patients.In June 2023,2023 ESH Guidelines for the management of arterial hypertension were released with updated recommendations for the timing of starting antihypertensive therapy.For patients with normal high-value blood pressure with prior cardiovascular disease,the guidelines recommend initiating antihypertensive therapy from 130/80 mmHg.The 2023 edition of the Chinese Guidelines for the Prevention and Control of Hypertension also recommends that the target blood pressure for those with high and very high cardiovascular risk can be further reduced to less than 130/80 mmHg.This suggests that greater clinical benefit can be achieved from intensive blood pressure control in hypertensive patients with comorbid cardiovascular disease.In recent years,multiple studies have shown the advantages of intensive blood pressure management in hypertensive patients.In this article,the progress in clinical studies related to intensive blood pressure control in hypertensive populations complicated with different cardiovascular diseases was reviewed,aiming to provide insight and evidence for intensive antihypertensive treatment in these patients.
关键词
高血压/强化降压/冠心病/心力衰竭/心房颤动Key words
Hypertension/Intensive antihypertensive treatment/Coronary heart disease/Heart failure/Atrial fibrillation引用本文复制引用
基金项目
陕西省重点研发计划国际科技合作计划(2023-GHYB-12)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据