宫颈腺癌与宫颈鳞状细胞癌患者筛查史特点的对比分析
Comparison of characteristics of cervical cancer screening history between cervical adenocarcinoma and cervical squamous cell carcinoma
叶敏娟 1李静 2陈梓菲 1何俊贤 1陈利发 1张宇1
作者信息
- 1. 510630 广州,中山大学附属第三医院妇产科
- 2. 518047 深圳,深圳市妇幼保健院妇科
- 折叠
摘要
目的 对比分析宫颈腺癌与宫颈鳞状细胞癌患者的宫颈癌筛查史特点,初步评价宫颈癌筛查方案对宫颈腺癌癌前病变的筛查效力.方法 回顾性分析 117 例宫颈腺癌和 712 例宫颈鳞状细胞癌患者的临床资料,对比 2 组不同病理类型宫颈癌患者在既往宫颈癌筛查史上的差异.结果 宫颈腺癌患者曾参与宫颈癌筛查的比例为 24.5%,高于宫颈鳞状细胞癌患者的 6.8%(P<0.001),且宫颈腺癌患者进行规范或高于规范频次筛查的比例为 18.4%,高于宫颈鳞状细胞癌患者的2.8%(P<0.001).宫颈鳞状细胞癌患者由于症状就诊的比例为91.6%高于宫颈腺癌患者的79.1%(P<0.001),早期宫颈腺癌患者中因宫颈筛查结果异常就诊的比例为 24.6%,高于早期宫颈鳞状细胞癌患者的 11.1%(P = 0.004),宫颈腺癌中早期患者因筛查结果异常就诊的比例为 24.6%,高于晚期患者的 4.0%(P = 0.022).结论 宫颈癌筛查方案对宫颈鳞状细胞癌的癌前病变筛查效力较高,对宫颈腺癌的癌前病变筛查效力较低,但有助于宫颈腺癌早期病例的诊断,因此应重视宫颈癌筛查,宫颈癌筛查方案有待进一步优化.
Abstract
Objective To comparatively analyze the characteristics of cervical cancer screening history between patients with cervical adenocarcinoma and cervical squamous cell carcinoma,and to preliminarily evaluate the efficacy of cervical cancer screening for precancerous lesions of cervical adenocarcinoma.Methods Clinical data of 117 patients with cervical adenocarcinoma and 712 patients with cervical squamous cell carcinoma were retrospectively analyzed,and the differences in cervical cancer screening history were statistically analyzed between two groups.Results The proportion of cervical adenocarcinoma patients receiving cervical cancer screening was 24.5%,significantly higher than 6.8%of those with cervical squamous cell carcinoma(P<0.001).The proportion of cervical adenocarcinoma patients receiving regular screening or above was 18.4%,significantly higher than 2.8%of those with cervical squamous cell carcinoma(P<0.001).The proportion of symptom-detected cervical squamous cell carcinoma was 91.6%,significantly higher than 79.1%of their counterparts with cervical adenocarcinoma cell carcinoma(P<0.001).The proportion of screening-detected stageⅠ-ⅡA cervical adenocarcinoma was 24.6%,significantly higher than 11.1%of those with screening-detected stage Ⅰ-ⅡA cervical squamous cell carcinoma(P = 0.004).The proportion of screening-detected stageⅠ-ⅡA cervical adenocarcinoma was 24.6%,significantly higher than 4.0%of those with screening-detected stageⅡB-Ⅳ cervical adenocarcinoma(P = 0.022).Conclusions Current cervical cancer screening regimen yields higher efficacy for precancerous lesions of cervical squamous cell carcinoma compared with cervical adenocarcinoma.However,it still contributes to the diagnosis of early cervical adenocarcinoma.Therefore,extensive attention should be paid to cervical cancer screening.Cervical cancer screening regimen remains to be further optimized.
关键词
宫颈腺癌/宫颈鳞状细胞癌/宫颈癌筛查/癌前病变Key words
Cervical adenocarcinoma/Cervical squamous cell carcinoma/Cervical cancer screening/Precancerous lesion引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据