儿童重症肺炎支原体肺炎诊疗建议——中山大学附属第三医院儿童重症肺炎支原体肺炎临床诊疗规范

Recommendations for diagnosing and treating severe Mycoplasma pneumoniae pneumonia in children:clinical practice protocols from the Third Affiliated Hospital of Sun Yat-sen University

杨可鑫 ¹潘莉 ¹曾锦清 ¹李中科 ¹李旭锋 ¹祝铃萍 ¹梁英 ¹杨丽芬 ¹张昆 ²戴敏 ³陈壮桂 ¹黎雅婷¹

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作者信息

1. 中山大学附属第三医院儿童医学中心,广东广州 510630;中山大学附属第三医院儿科重症监护室,广东广州 510630
2. 中山大学附属第三医院针灸科,广东广州 510630
3. 中山大学附属第三医院儿童医学中心,广东广州 510630;中山大学附属第三医院中医科,广东广州 510630
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摘要

肺炎支原体肺炎是我国 5 岁及以上儿童常见的社区获得性肺炎.尽管大多数患儿预后良好,但部分病例因病原体耐药或混合感染等因素发展为重症,生命受到严重威胁,并可能遗留不同程度的后遗症.中山大学附属第三医院儿童医学中心结合现行指南、共识和自身实践经验,提出了重症肺炎支原体肺炎治疗"412"集束化治疗策略,即抗感染、抗炎症风暴、抗凝和抗氧化应激治疗,中西医结合治疗,呼吸管理和随诊管理的集束化方案,为儿童重症肺炎支原体肺炎的诊疗提供参考.

Abstract

Mycoplasma pneumoniae pneumonia(MPP)is a common cause of community-acquired pneumonia in children aged 5 and older in China.Although most affected children have favorable clinical prognosis,some cases can escalate into severe MPP due to risk factors such as pathogen resistance or co-infections,etc.These severe cases significantly jeopardize the lives of children and may lead to diverse long-term sequelae.In response to this challenge,the Children's Medical Center of the Third Affiliated Hospital of Sun Yat-sen University,integrating current guidelines,expert consensus,and its extensive clinical experience,has devised the"412"cluster treatment strategy.This comprehensive approach encompasses treatments for anti-infection,anti-inflammatory storm,anticoagulation and antioxidant stress.Additionally,it seamlessly integrates traditional Chinese medicine with western therapies,featuring bundled respiratory management and follow-up care.This strategy provides a valuable reference for the diagnosis and treatment of severe MPP in children.

关键词

重症肺炎支原体肺炎/重症肺炎/儿童/集束化治疗

Key words

Severe Mycoplasma pneumoniae pneumonia/Severe pneumonia/Children/Cluster therapy

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基金项目

国家自然科学基金(32370191)

广东省自然科学基金(2019A1515011441)

广东省适宜技术推广项目(202303290932258761)

广东省医学科学技术研究基金(A2021386)

出版年

2024

新医学

中山大学

新医学

CSTPCD

影响因子：0.8

ISSN：0253-9802

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