多次静脉输液后出现严重过敏反应诊治一例
A case of severe allergic reaction following multiple intravenous infusion treatments
许凤 1张莉 1张虹婷 1石楚琪 1贾巧茹 1肖浩 1孟娟1
作者信息
- 1. 四川大学华西医院变态反应中心,四川 成都 610041;四川大学华西医院耳鼻咽喉头颈外科,四川 成都 610041
- 折叠
摘要
临床中进行静脉穿刺前必须使用表面消毒剂进行皮肤消毒.氯己定是常用的消毒剂,在静脉输液时氯己定随着穿刺针微量进入血液循环,可引起速发型(Ⅰ型)超敏反应.这种过敏反应常被误以为由输入的药物(如抗生素)所致,造成误诊和漏诊.文章报道 1 例多次静脉输液后出现过敏反应、经诊断为氯己定过敏并排除抗生素过敏的病例,以加强临床医师对氯己定过敏的认识.该例的诊治过程提示,当患者发生输液相关过敏反应时,临床医师应考虑氯己定过敏的可能.
Abstract
In clinical practice,the application of surface disinfectants for skin disinfection is a prerequisite for venipuncture.Chlorhexidine,a widely recognized disinfectant,is frequently employed for this purpose.However,during intravenous infusions,minute quantities of chlorhexidine can be inadvertently introduced into the bloodstream via the puncture needle,potentially precipitating immediate-type(type)hypersensitivity reactions.Regrettably,these reactions are often erroneously attributed to administered medications,such as antibiotics,which can result in both misdiagnosis and underdiagnosis.This article details a case of an allergic reaction that occurred subsequent to multiple intravenous infusions and was ultimately identified as chlorhexidine-induced after antibiotic allergy was ruled out.The objective of this report is to deepen the clinical physcians'comprehension of chlorhexidine-induced allergies in the context of infusion-related allergic reactions,thereby offering a valuable reference for accurate diagnosis and effective treatment strategies.
关键词
静脉输液/氯己定/过敏反应Key words
Intravenous infusions/Chlorhexidine/Allergic reactions引用本文复制引用
基金项目
国家临床重点专科建设项目(TJZ202303)
出版年
2024
国家科技期刊平台
NSTL
万方数据