Chinese translation and reliability and validity test of the Barriers to Growth Hormone Treatment
Objective:To localize the Barriers to Growth Hormone treatment(BAR-GHT)and test its reliability and validity in patients with dwarfism.Methods:Through translation,back-translation,cultural adjustment,and pre-experiment,the Chinese version of BAR-GHT was formed.A total of 216 patients with dwarfism who had received growth hormone treatment for more than 3 months and their parents were selected for the questionnaire survey to verify its reliability and validity.Results:The Chinese version of BAR-GHT included a parent version(16 items in 5 dimensions)and a child/adolescent version(17 items in 5 dimensions).The Cronbach's αcoefficients of the scales were 0.876 and 0.905,the split-half reliability was 0.852 and 0.793,and the test-retest reliability was 0.857 and 0.934,respectively.The scale-level content validity index was 0.921 and 0.933,and the criterion-correlated validity with the 8-item Morisky Medication Adherence Scale was 0.597 and 0.703(all P<0.01),respectively.Exploratory factor analysis extracted 5 common factors,and the cumulative variance contribution rates were 82.442%and 81.433%,respectively.Conclusions:The Chinese version of BAR-GHT has good reliability and validity,which can be used to assess the level of growth hormone treatment barriers among patients with dwarfism in China.