徐州医科大学学报2024,Vol.44Issue(2) :124-130.DOI:10.3969/j.issn.2096-3882.2024.02.008

三叉神经痛球囊压迫术后复发的影响因素分析

Analysis of influencing factors for recurrence of trigeminal neuralgia after balloon compression

沈志远 刘雨昂 王常州 李沛隆 吴金霞 王秀存
徐州医科大学学报2024,Vol.44Issue(2) :124-130.DOI:10.3969/j.issn.2096-3882.2024.02.008

三叉神经痛球囊压迫术后复发的影响因素分析

Analysis of influencing factors for recurrence of trigeminal neuralgia after balloon compression

沈志远 1刘雨昂 1王常州 1李沛隆 1吴金霞 2王秀存3
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作者信息

  • 1. 徐州医科大学研究生院,江苏徐州 221004
  • 2. 徐州医科大学生理学教研室
  • 3. 徐州医科大学附属医院神经外科,江苏徐州 221002
  • 折叠

摘要

目的 分析球囊压迫术(PBC)治疗原发性三叉神经痛(PTN)术后复发的相关影响因素.方法 回顾性分析2020年8月-2022年8月徐州医科大学附属医院首次接受PBC治疗的108例PTN患者的临床资料.根据随访情况将患者分为复发组和未复发组,收集患者术前、术中、术后资料,分析疼痛复发的相关影响因素.结果 术后随访12~36个月,17例(15.74%)术后疼痛复发,复发时间为术后1~18个月.单因素分析结果显示,2组高血压、压迫时间≤2 min、术后即刻面部麻木评分(Ⅰ+Ⅱ)的差异有统计学意义(P<0.05),其余资料差异均无统计学意义(P>0.05).将单因素分析中有统计学意义的资料经Cox回归模型分析显示,高血压、术后即刻面部麻木程度是PBC术后疼痛复发的危险因素(P<0.05).将患者有无高血压及术后即刻面部麻木评分2项资料分别进行Kaplan-Meier法生存分析,结果显示高血压及术后即刻面部麻木程度越轻的患者随时间的增加其复发概率越大(P<0.05).结论 高血压和术后即刻面部麻木程度是PBC治疗PTN术后疼痛复发的危险因素.

Abstract

Objective To analyze the influencing factors related to the postoperative recurrence of primary trigeminal neuralgia(PTN)treated with percutaneous balloon compression(PBC).Methods The clinical data of 108 PTN patients who initially received PBC in the Affiliated Hospital of Xuzhou Medical University from August 2020 to August 2022 were retrospectively analyzed.According to the follow-up,the patients were divided into two groups:a recurrence group and a non-recurrence group.Their preoperative,intraoperative and postoperative data were collected to analyze the influencing factors of pain recurrence.Results During the follow-up period of 12-36 months,17 patients(15.74%)had recurrence of pain,and the time of recurrence ranged from 1 to 18 months after surgery.The results of univariate analysis showed that the differences between the two groups were statistically significant(P<0.05)for hypertension,compression time≤2 min,and immediate postoperative facial numbness scores(Ⅰ+Ⅱ),while the differences in the other data were not statistically significant(P>0.05).The Cox regression model analysis using the statistically significant data in the univariate analysis showed that hypertension and the degree of facial numbness in the immediate postoperative period were risk factors for the recurrence of postoperative pain in PBC(P<0.05).The Kaplan-Meier method was used to analyze the survival of patients with and without hypertension and immediate postoperative facial numbness score,and the results showed that the probability of recurrence of PBC pain increased over time in patients with hypertension and less immediate postoperative facial numbness(P<0.05).Conclusions Hypertension and immediate postoperative facial numbness are risk factors for the recurrence of postoperative pain in PTN treated with PBC.

关键词

原发性三叉神经痛/球囊压迫术/疼痛复发/Cox回归模型/Kaplan-Meier法

Key words

primary trigeminal neuralgia/percutaneous balloon compression/pain recurrence/Cox regression model/Kaplan-Meier method

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基金项目

国家自然科学基金(81802529)

江苏省高等学校创新创业训练计划(202110313047Y)

出版年

2024
徐州医科大学学报
徐州医学院

徐州医科大学学报

CSTPCD
影响因子:0.395
ISSN:2096-3882
参考文献量25
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