Clinical study of F-NLR score to assess the short-term prognosis of patients with spontaneous basal ganglia hemorrhage
Objective To investigate the role of the combined peripheral blood fibrinogen and neutrophil/lymphocyte ratio score(F-NLR)in predicting the short-term prognosis of spontaneous basal ganglia hemorrhage.Methods A total of 154 patients with spontaneous basal ganglia hemorrhage who were admitted from January 2021 to December 2022 were enrolled and their clinical data were retrospectively analyzed.The patients were evaluated by the modified Rankin Scale(mRS).According to their prognosis,they were divided into two groups:a good prognosis group(n=50)and a poor prognosis group(n=104).The risk factors for basal ganglia hemorrhage were analyzed by univariate and multivariate regression.A ROC curve was plotted to evaluate the predictive value of F-NLR for the prognosis of patients with basal ganglia hemorrhage.Results There were statistical differences in age,hematoma volume,whether it broke into the ventricle,GCS score,white blood counts,absolute neutrophil count(ANC),absolute lymphocyte count(ALC),neutrophil/lymphocyte ratio(NLR),fibrinogen(FIB),and F-NLR between the two groups(P<0.05).Multivariate logistic regression analysis showed that the hematoma volume of basal ganglia hemorrhage,Glasgow Coma Scale(GCS)score,high WBC,low ALC,and high F-NLR scores were important independent risk factors for poor short-term prognosis for patients with basal ganglia hemorrhage(P<0.05).The ROC curve indicated that the AUC value of F-NLR score for predicting the poor prognosis of basal ganglia hemorrhage was 0.799(95%CI:0.723-0.874),with a sensitivity of 66.3%and a specificity of 86.0%.Conclusions The F-NLR score is an important marker for predicting the prognosis of patients with basal ganglia hemorrhage,which can provide reference for future clinical application.
NETL
NSTL
万方数据
维普
