首页|耳穴压豆联合针灸治疗对经皮冠状动脉介入术后抑郁患者血清炎性因子与神经递质的影响

耳穴压豆联合针灸治疗对经皮冠状动脉介入术后抑郁患者血清炎性因子与神经递质的影响

Effect of auricular point pressing beans combined with acupuncture and moxibustion on serum inflammatory factors and neurotransmitters in patients with depression after percutaneous coronary intervention

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目的 探究耳穴压豆结合针灸对经皮冠状动脉介入术(percutanous coronary intervention,PCI)后抑郁患者血清炎性因子与神经递质的影响.方法 收集陕西中医药大学附属医院2021年1月至2023年1月收治的88例PCI术后抑郁患者,随机分为对照组(44例,针灸)、联治组(44例,耳穴压豆+针灸),评估两组患者疗效、抑郁、焦虑情况,测量对比治疗前及治疗后组间血清炎性因子、神经递质水平,记录不良反应.结果 联治组治疗后总有效率显著高于对照组(P<0.05);治疗后,联治组汉密尔顿焦虑量表(hamilton anxiety scale,HAMA)及汉密尔顿抑郁量表(hamilton depression scale,HAMD)评分均显著低于对照组(P<0.05);血清白介素-6(interleukin-6,IL-6)、C反应蛋白(C-reactive protein,CRP)水平显著低于对照组(P<0.05);血清5-羟色胺(5-hydroxy tryptamine,5-HT)及去甲肾上腺素(Norepinephrine,NE)水平显著高于对照组(P<0.05);两组不良反应总发生率比较差异无统计学意义(P>0.05).结论 耳穴压豆联合针灸治疗PCI术后抑郁可有效地调节患者血清炎性因子与神经递质水平,改善其焦虑、抑郁情绪,疗效确切,安全性高.
Objective To explore the effect of auricular point pressing beans combined with acupuncture and moxibustion on serum inflammatory factors and neurotransmitters in depressed patients after percutaneous coronary intervention(PCI).Methods A total of 88 post-PCI depression patients admitted to the Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine from January 2021 to January 2023 were collected and randomly divided into a control group(44 cases,acupuncture)and a combined treatment group(44 cases,auricular point pressure bean + acupuncture).The curative effect and patients' depression and anxiety,measure were evaluated and the levels of serum inflammatory factors and neurotransmitters between the two groups before and after treatment were compared,and adverse reactions were recorded.Results The total effective rate of the combined treatment group was significantly higher than that of the control group(P<0.05).After treatment,the scores of Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD)in the combined treatment group were significantly lower than that of the control group(P<0.05);the levels of serum interleukin-6(IL-6)and C-reactive protein(CRP)in the combined treatment group after treatment were significantly lower than those of the control group(P<0.05);the levels of serum 5-hydroxytryptamine(5-HT)and norepinephrine(NE)in the combined treatment group were significantly higher than those in the control group(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Auricular point pressure beans combined with acupuncture and moxibustion for post-PCI depression can effectively regulate the levels of serum inflammatory factors and neurotransmitters in patients,and improve their anxiety and depression.It is effective and safe.

Auricular point pressure beansAcupuncture and moxibustionPercutaneous coronary interventionDepressionInflammatory factorsNeurotransmitters

房瑛、王晓伟、赵晓芸、刘婷、赵海浪

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陕西中医药大学附属医院急诊科,陕西 咸阳 712000

陕西中医药大学第二附属医院急救中心,陕西 咸阳 712000

西安建筑科技大学校医院中医科,陕西 西安 710000

陕西中医药大学第二附属医院耳鼻喉科,陕西 咸阳 712000

陕西中医药大学第二附属医院急诊科,陕西 咸阳 712000

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耳穴压豆 针灸 经皮冠状动脉介入术 抑郁 炎性因子 神经递质

咸阳市科技成果推广计划

2020KT-06

2024

延安大学学报(医学科学版)
延安大学

延安大学学报(医学科学版)

影响因子:0.551
ISSN:1672-2639
年,卷(期):2024.22(1)
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