Mechanism of ginsenoside Rh2 in the treatment of pulmonary fibrosis based on network pharmacology and molecular docking
In order to explore the mechanism of ginsenoside Rh2 in the treatment of pulmonary fibrosis,using network pharmacology and molecular docking technique to predict the potential targets.The results of network pharmacology show that ginsenoside Rh2 has 70 targets,pulmonary fibrosis has 2963 targets,50 intersecting genes and 10 core targets for drug treatment of disease.Ginsenoside Rh2 has 122 biological pathways and 361 functional analyses in the treatment of pulmonary fibrosis.The results of molecular docking show that ginsenoside Rh2 exhibit stable binding activity with the nine core targets.These studies suggests that ginsenoside Rh2 may participate in the treatment of pulmonary fibrosis through multiple targets and pathways,and the results of this study can provide references for the subsequent investigation of ginsenoside Rh2 treatment of pulmonary fibrosis.
万方数据
维普
