Clinical analysis of 38 cases of advanced epithelial ovarian cancer treated by neoadjuvant chemotherapy combined with cytoreductive surgery
BACKGROUND To observe the efficacy and safety of neoadjuvant chemotherapy combined with cytoreductive surgery in the treatment of advanced epithelial ovarian cancer.CASE REPORTS A total of 76 patients with advanced epithelial ovarian cancer admitted from April 26,2015 to April 26,2016 were selected as the study subjects and randomly divided into control group and observation group,with 38 patients in each group.The control group was treated with cytoreductive surgery,while the observation group was treated with neoadjuvant chemotherapy combined with cytoreductive surgery.The clinical efficacy and safety of the treatment methods were compared between the two groups.The results showed that the remission rate of patients in the observation group was 71.1%,which was significantly higher than 42.1%of patients in the control group(P＜0.05).But the incidence of moderate and severe adverse reactions in observation group was significantly higher than that of control group(P＜0.05).DISCUSSION Neoadjuvant chemotherapy combined with cytoreductive surgery in the treatment of advanced epithelial ovarian cancer can improve the efficacy,but the incidence of adverse reactions is higher.
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