首页|艾滋病营养缺乏患者的营养支持结合抗逆转录病毒治疗效果观察

艾滋病营养缺乏患者的营养支持结合抗逆转录病毒治疗效果观察

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目的:分析营养支持+抗逆转录病毒疗法治疗艾滋病营养缺乏的效果.方法:选取2022年1月—12月在厦门大学附属第一医院感染科就诊的82例艾滋病初治合并营养缺乏的患者,以随机数字表法分为对照、观察两组,分别实施抗逆转录病毒治疗、抗逆转录病毒治疗+营养支持治疗,6个月后对比效果.结果:治疗后观察组病毒载量低于对照组(P<0.05).观察组治疗后大便次数较少,且止泻时间较短(P<0.05).治疗后观察组患者营养指标改善效果优于对照组(P<0.05).治疗前,两组免疫功能差异不显著(P>0.05),治疗后,两组CD8+水平差异不显著(P>0.05),观察组患者CD4+水平高于对照组(P<0.05).治疗后观察组生活质量评分较高(P<0.05).结论:艾滋病营养缺乏患者抗逆转录病毒治疗期间,配合营养支持可促进机体营养水平提高,并提高免疫力.
Observation on the effect of nutritional support combined with antiretroviral therapy on AIDS patients with nutritional deficiency
Objective:To analyze the effect of nutritional support combined with antiretroviral therapy on AIDS patients with nutritional deficiency.Methods:A total of 82 cases of AIDS initial treatment combined with nutritional deficiency patients from the Infection Department of the First Affiliated Hospital of Xiamen University from January 2022 to December 2022 were selected.They were divided into control group and observation group by random number table method.They were treated with antiretroviral therapy,antiretroviral therapy+nutritional support therapy,respectively.The effects were compared 6 months later.Result:After treatment,the viral load of the observation group was lower than that of the control group(P<0.05),the observation group had fewer bowel movements and a shorter time to stop diarrhea(P<0.05),and the improvement effect of nutritional indicators in the observation group was better than that in the control group(P<0.05).Before treatment,there was no significant difference in immune function between the two groups(P>0.05).After treatment,there was no significant difference in CD8+levels between the two groups(P>0.05),while the CD4+levels in the observation group were higher than those in the control group(P<0.05).After treatment,the observation group had a higher quality of life score(P<0.05).Conclusion:During the antiretroviral therapy for AIDS patients with nutritional deficiency,nutritional support can promote the nutritional level of the body and enhance immunity.

AIDSNutritional deficiencyNutritional supportAntiretroviral therapy

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厦门大学附属第一医院感染科,福建 厦门 361000

艾滋病 营养缺乏 营养支持 抗逆转录病毒治疗

2024

延边大学医学学报
延边大学

延边大学医学学报

影响因子:0.308
ISSN:1000-1824
年,卷(期):2024.47(3)