Observation of Pneumocystis jiroveci pneumonia in patients after renal transplantation
Objective To observe the incidence of Pneumocystis jiroveci pneumonia(PJP)in patients after renal transplantation.Methods:Sixty patients with PJP after renal transplantation in the Second Affiliated Hospital of Nanhua University from June 2021 to May 2024 were selected as the research objects.The clinical data of these patients were retrospectively analyzed.Results The levels of CD4+auxillary/induced T lymphocytes and CD3+total lymphocytes of these patients were higher at discharge than at admission(P<0.05),while the levels of lactate dehydrogenase(LDH),1-3-β-D-glucan(G-test)and C-reactive protein(CRP)were lower at discharge than at admission(P<0.05).There was no significant difference in white blood cell(WBC)count and procalcitonin(PCT)level between discharge and admission(P>0.05).The cure rate for these patients was 100%,and the overall incidence of complications was 18.33%(11/60).Conclusion CT examination of lung combined with PCR detection of Pneumocystis jiroveci in sputum can detect the early lesions of PJP patients,and the cure rate can be improved under the condition of rational drug use,but the occurrence of complications should be vigilant.
Pneumocystis jiroveci pneumoniarenal transplantationclinical diagnosis and treatment