Characteristics of pathogenic bacteria distribution,blood glucose level and inflammatory factors changes in elderly patients with type 2 diabetes mellitus complicated with urinary tract infection
Objective To investigate the distribution of pathogenic bacteria,blood glucose level and inflammatory factors changes in elderly patients with type 2 diabetes mellitus(T2DM)complicated with urinary tract infection.Method A total of 70 patients admitted to Wuxi Mingci Cardiovascular Disease Hospital were selected.34 patients with urinary tract infections were included in the infected group,and 36 patients without urinary tract infection were classified as the uninfected group.White blood cell count(WBC)and neutrophil count(NEU)of the patients were observed,and fasting blood glucose(FBG),2-hour postprandial blood glucose(2hPG),glycated hemoglobin(HbA1c),interleukin-6(IL-6),tumor necrosis factor alpha(TNF-α),C-reactive protein(CRP),urine bacterial count,white blood cell count and red blood cell count were detected.The pathogenic bacteria were isolated,cultured and identified in the infected group.Results The peripheral blood WBC,NEU,and urinary bacterial count in the infected group were higher than those in the uninfected group(P＜0.05).32 strains were cultured in the infected group,mainly Escherichia coli(62.5%,20 strains).The levels of FBG,2hPG,and HbA1c in the infected group were higher than those in the uninfected group(P＜0.05).The levels of IL-6,TNF-α and CRP inflammatory factors in the infected group were higher than those in the uninfected group(P＜0.05).Conclusion When elderly T2DM patients are complicated with urinary tract infections,peripheral blood indicators WBC,NEU and urinary bacterial count are increased,and the pathogenic bacteria are mainly Escherichia coli.The levels of inflammatory factors such as IL-6,TNF-α and CRP and blood glucose levels are increased,which requires timely and rational use of antibiotics.
type 2 diabetes mellitusurinary tract infectionblood glucose
万方数据
维普
