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复方磺胺甲唑治疗儿童百日咳的效果

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目的:探讨使用复方磺胺甲唑治疗儿童百日咳的临床效果.方法:选择自2020年1月至2024年6月间北京儿童医院新疆医院收治的100例儿童百日咳患儿,采用随机数表法分为对照组及观察组,每组各50例.对照组患儿应用大环内酯类药物进行治疗,观察组应用复方磺胺甲唑进行治疗.比较两组患儿临床症状持续时间及疗效.结果:观察组患儿夜间咳嗽、咳嗽后呕吐、咳嗽时面红及痉挛性咳嗽的持续时间均明显短于对照组(P<0.05).观察组治疗总有效率明显高于对照组(P<0.05).结论:相比于大环内酯类药物,使用复方磺胺甲唑治疗儿童百日咳的效果更好,可显著提高治疗总有效率,缩短其临床症状的持续时间,可为儿童百日咳患儿提供较高效的治疗选择.
The effect of compound sulfamethoxazole in the treatment of pertussis in children
Objective:To explore the clinical efficacy of using compound sulfamethoxazole to treat pertussis in children.Methods:100 pediatric pertussis patients admitted to Xinjiang Hospital were selected from January 2020 to June 2024,and were divided into observation group and control group by using random number table method,with 50 in each group.The control group was treated with macrolide drugs,while the observation group was treated with compound sulfamethoxazole.The duration of clinical symptoms and curative effect were compared between the two groups.Results:The duration of nocturnal cough,vomiting after coughing,facial flushing during coughing,and spasmodic cough in the observation group were significantly shorter than those in the control group(P<0.05).The total effective rate of treatment was significantly higher than that of the control group(P<0.05).Conclusion:Compared to macrolide drugs,the compound sulfamethoxazole is more effective in treating children with pertussis,significantly improving the overall treatment efficacy and shortening the duration of clinical symptoms,which provides a more efficient treatment option for children with pertussis.

Pertussis in childrenCompound sulfamethoxazoleMacrolide drugs

亚克普·艾海提、哈斯也提不韦·依拉英

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北京儿童医院新疆医院,新疆 乌鲁木齐 831399

儿童百日咳 复方磺胺甲唑 大环内酯类药物

2024

延边大学医学学报
延边大学

延边大学医学学报

影响因子:0.308
ISSN:1000-1824
年,卷(期):2024.47(4)