A CFD simulation method for rotameter based on the 6DOF model and the working principle of rotameter was pro-posed in this paper to address the issues of low accuracy of low flow rate measurement.Based on this simulation method,a rotame-ter for water flow detection with flow range of 60~600 mL/h was designed.The results show that the performance of the rotameter is optimized when the cone half angle of the cone tube is 0.1° and the float diameter is 2.98 mm.The feasibility of the design scheme is verified through actual flow experiments.