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乳腺癌中P53,nm23蛋白的表达及临床病理意义

The Expression of the P53 & nm23 Protein in Breast Cancer and its Clinical Pathological Significance

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目的探讨乳腺癌中P53,nm23蛋白表达水平及临床病理意义。方法采用免疫组化方法对原发乳腺癌标本进行P53和nm23蛋白检测,检测结果按照年龄、肿物大小、病理学分型、分化程度和淋巴结转移等分组统计分析,组间显著性差异采用x2检验。结果 P53蛋白阳性表达与患者年龄、肿物大小和淋巴结转移无关,但与乳腺癌病理学分型和分化程度关联密切;nm23蛋白表达与患者年龄、癌肿病理分型及分化程度无关,但与癌肿大小和转移有密切关联。结论根据nm23检测结果筛选具有转移危险的患者,早期实施化、放疗;根据P53检测结果,早期预
Objective To explore the expression level of the p53 nm23 protein in breast cancer and its clinical pathological significance.Methods After the p53 an nm23 protein test,patients were statistically classified according to age,size of the tumor,pathological

breast cancerp53nm23clinical pathology

乳腺癌 P53 nm23 临床病理

2011

雁北师范学院学报
雁北师范学院

雁北师范学院学报

ISSN:1009-1939
年,卷(期):2011.27(3)