首页|小剂量糖皮质激素联合茶碱治疗老年哮喘的疗效观察

小剂量糖皮质激素联合茶碱治疗老年哮喘的疗效观察

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目的:分析小剂量糖皮质激素联合茶碱治疗老年哮喘的疗效。方法:研究对象选取本院2011年6月至2013年4月收治的80例老年哮喘患者,随机方法分组。参照组患者接受小剂量糖皮质激素治疗,试验组患者接受小剂量糖皮质激素联合茶碱治疗。连续治疗3个月,对比分析两组患者治疗前后肺功能的变化、治疗期间不良反应发生率的差异性。结果:经过治疗后所有患者第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、肺活量(VC)、呼气峰流速(PEF)等指标均较治疗前提高,其中试验组各指标改善幅度明显大于参照组,差异有统计学意义(P<0.05)。试验组患者治疗期间不良反应发生率跟参照组相比,差异无统计学意义(P>0.05)。结论:小剂量糖皮质激素联合茶碱治疗老年哮喘可改善患者肺功能,且不良反应少,具有较高的安全性,值得推广。
objective to analyze the joint theophylline dose glucocorticoid treatment the curative effect of elderly asthma. Selection method of object of study in June 2011 to April 2011 at our hospital treated 80 cases of elderly patients with asthma, random grouping method. Control group patients received low- dose glucocorticoids treatment, the experimental group patients received low- dose glu-cocorticoids with theophyl ine therapy. Treatment for3 months in a row, comparative analysis of two groups before and after treatment in patients with pulmonary function changes, the incidence of adverse reactions during the period of treatment differences. The results of All of the patients after treatment of forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), forced vital capacity (VC), peak expiratory flow (PEF), and other indicators was improved, the group of indicators improved significantly greater than the control group, the difference was statistically significant (P< 0.05). Incidence of adverse reactions during experimental group patients compared with control group, there was no statistically significant difference (P > 0.05). Conclusion low- dose glucocorticoids with theophylline therapy in elderly patients with asthma can improve lung function, and less adverse reaction, has the high security, is worth promoting.

glucocorticoidTheophylline. AsthmaClinical curative effect

嵇立兵、徐左平

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江苏省建湖县中医院呼吸科 224700

糖皮质激素 茶碱 哮喘 临床疗效

2015

延边医学

延边医学

ISSN:
年,卷(期):2015.(3)
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