Objective:appendicitis application of open and laparoscopic appendectomy curative effect comparison of acute perfora-tion. Method:select our hospital 80 cases of perforated appendicitis patients as the research object, which is divided into the observation group and the control group, the control group to implement the open appendectomy treatment, the observation group laparoscopic appendectomy, the basic situation of operation were compared between two groups. Results: the observation group compared to the control group, the operation time is long, short hospital stay, hospital costs high, anal exhaust and early ambulation, less complications. Conclusion:the application of laparoscopy in the treatment of perforated appendicitis, with small trauma, fewer complications, faster re-covery and other characteristics, which belongs to the safe and effective treatment, it is worth clinical popularizing and applying.