首页|吡格列酮联合克罗米芬治疗多囊卵巢综合征40例的临床分析

吡格列酮联合克罗米芬治疗多囊卵巢综合征40例的临床分析

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目的::探讨吡格列酮联合克罗米芬治疗多囊卵巢综合征的临床疗效。方法:选择我院收治的40例多囊卵巢综合征患者为研究对象,以临床治疗方案的不同将其定义为对照组与观察组,每组20例,对照组患者给予克罗米芬治疗,观察组患者给予吡格列酮联合克罗米芬治疗,观察两组患者的治疗效果。结果:观察组治疗效果明显高于对照组,p<0.05;且治疗后黄体生成激素、卵泡刺激素、空腹胰岛素、卵巢大小、卵泡数目的变化情况也明显优于对照组患者,p<0.05,差异具有统计学意义。结论:吡格列酮联合克罗米芬治疗多囊卵巢综合征的临床疗效显著,可以改善患者卵巢的状况以及激素水平,提高患者的生存质量,值得在临床实践中广泛的应用和推广。
Objective:To investigate the clinical effect of pioglitazone combined with clomiphene in treatment of polycystic ovary syndrome. Methods:in our hospital treated 40 cases of polycystic ovary syndrome patients as the research object, in the clinical treatment of different which is defined as the control group and the observation group, 20 cases in each group, the control group were treated with clomiphene treatment, observation group were treated with pioglitazone combined with clomiphene Fen treatment, two groups were observed in patients with therapeutic effect. Results: the therapeutic effect of observation group is obviously higher than the control group, P<0.05;and after treatment with luteinizing hormone, follicle stimulating hormone, fasting insulin, ovarian size, fol icle number changes are also significantly better than the patients in the control group, P<0.05, with significant difference. Conclusion:pioglitazone combined with clomiphene significant therapeutic effect in the treatment of polycystic ovary syndrome, can improve the patients with ovarian status and hormone levels, improve the quality of life of patients, is worthy of wide range of application and promotion in clinical practice.

pioglitazoneclomiphene citratepolycystic ovary syndromeclinical effect

张敏、张艳

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安徽省亳州市人民医院 236000

吡格列酮 克罗米芬 多囊卵巢综合征 临床疗效

2015

延边医学

延边医学

ISSN:
年,卷(期):2015.(4)
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