Objectives Objective To study the effectiveness of Minimal y invasive- Posterior lumbar interbody fusion (MIS- PLIF) with percutaneous long- arm pedicle screw fixation for the treatment of central- type lumbar disc herniation and stenosis. Methods From April 2012 to April 2014, we retrospectively analyzed 49 cases, who underwent MIS- PLIF combined with percuta-neous long- arm pedicle screw fixation for central- type lumbar disc herniation and spinal stenosis. Statistical parameters included:opera-tion time, blood loss, postoperative hospital stay, complications;VAS and JOA scores 1 week, 3 months, 12 months postoperatively, as well as fusion rate at the last follow- up. Results Postoperative follow- up ranged 5 ~18 months, on average 11 months. The average operation time was 117 ± 20 min, average blood loss was 113 ± 39 ml. Average postoperative hospital stay was 7 days. The postoper-ative VAS and JOA scores were statistically different from those before surgery (P<0.05). 91%of patients had solid fusion at the last fol-low- up. No screw loosening and rod breakage was noted. Conclusion:MIS- PLIF with percutaneous long- arm pedicle screw fixation for the treatment of central- type lumbar disc herniation and spinal stenosis had the advantages of intraoperative exposed fully, minimal trauma, less bleeding, fewer complications, and reduced postoperative pain.