摘要
目的：分析探讨甲巯咪唑联合比索洛尔治疗甲亢的临床效果。方法：回顾性分析我院自2012年1月~2013年1月期间收治的68例甲亢患者的临床资料，随机分为对照组和治疗组，各组34例，比较两组的临床效果及不良反应发生情况。结果：治疗组痊愈17例（50.00%）、显效12例（34.29%）、有效3例（5.88%）、无效2例（5.88%），总有效率32（94.12%）；对照组痊愈8例（23.53%）、显效13例（38.24%）、有效5（14.71%）、无效8例（5.88%），总有效率26（76.47%），治疗组总有效率显著高于对照组，两组比较差异有统计学意义（P<0.05）。结论：甲巯咪唑联合比索洛尔治疗甲亢的临床疗效显著，安全性高，不良反应少，值得临床推广应用。
Abstract
Objective:To analyze the clinical effects of the treatment for hyperthyroidism by methimazole and bisoprolol. Methods:68 patients who suffered from the hyperthyroidism and who accepted treatment in our hospital from January 2012 to January 2013 were taken as the research objects, and these patients were randomly divided into the control group and the observation group, with 34 pa-tients in each group. Then, the clinical effects and the occurrence situations of adverse reactions of these two groups were compared. Outcome:In the observation group, 17 of patients were cured(50.00%), 12 of patients had evident effect (34.29%), 3 of patients had ef-fects (5.88%), 2 of patients had no effects (5.88%), and the whole effective rate was 94.12%. However, in the control group, 8 of patients were cured(23.53%), 13 of patients had evident effect (38.24%), 5 of patients had effects (14.71%), 8 of patients had no effects (5.88%), and the whole effective rate was 76.47%.Thus, the whole effective rate in the observation group was evidently higher than that in the control group and the differences had the statistical significance (P<0.05). Conclusion: The clinical effects of the treatment for hyper-thyroidism by methimazole and bisoprolol are evident, which have high safety and few adverse reactions. Thus, it should be promoted in the clinic applications.
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